Nicotinamide Riboside Chloride Powder CAS.23111-00-4 99%
Product Name: Nicotinamide Riboside Chloride
CAS No: 23111-00-4
Molecular Weight:C₁₁H₁₅ClN₂O₅
Molecular Formula:290.70 g/mol
Capacity: 500kgs per month
Source: synthetic
Purity (HPLC) >99.0%
Place of Origin: China Yinherb-Lab
Packing: As per client's requirements
Minimum Order Quantity: 1kg
Storage: Store in cool & dry place, Keep away from strong light and heat for 2 years
Description
Xi’an Yinherb Bio-Tech Co., Ltd. is one of the leading manufacturers and suppliers of nicotinamide riboside chloride powder cas.23111-00-4 99% in China, also supports customized service. Welcome to buy bulk nicotinamide riboside chloride powder cas.23111-00-4 99% for sale here from our factory. Quality products and reasonable price are available.
Leading Research lab on Nutritional Supplements in China
Yinherb Lab is a professional research Lab in china, have focused on Nutritional Supplements, Nootropics and Peptide raw materials researching and producing in this market for over 10 years with stable quality and great reputations, we can supply every batch test, including COA, HPLC and NMR. I believe that we must work well in future.
Yinherb Lab High Quality Nicotinamide Riboside Chloride Powder CAS.23111-00-4 99%
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Product name |
Nicotinamide Riboside Chloride (NRC) |
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Other name |
1-[(2R,3R,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)oxolan-2-yl]pyridin-1-ium-3-carboxamide chloride |
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CAS No. |
23111-00-4 |
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Molecular formula |
C₁₁H₁₅ClN₂O₅ |
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Molecular weight |
290.70 g/mol |
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Purity |
Typically ≥95% (pharmaceutical grade ≥99%) |
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Appearance |
White to off-white crystalline solid |
| Solubility | Soluble in water, DMSO, DMF; insoluble in ethanol |
| Storage | 2–8°C, sealed; stable for ≥2 years |
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Packing |
1kg per bag 25kg per drum |
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Application |
Nutritional Supplements |
What is Nicotinamide Riboside Chloride Powder?
Nicotinamide Riboside Chloride (NRC, NR-Cl, CAS 23111-00-4) is an orally active vitamin B3 derivative and NAD+ precursor that safely boosts NAD+ levels, activates sirtuins, and supports mitochondrial function, with broad applications in anti-aging, metabolic health, and neuroprotection.
NRC vs. NAM: NRC avoids the feedback inhibition that limits NAM's NAD⁺ boosting ability, making it far more effective for activating sirtuins (key for anti-aging and metabolic health).
NRC vs. NA: NRC lacks the flushing side effect of NA, allowing for higher, more consistent doses without discomfort.
NRC vs. NMN: NMN is slightly more potent at boosting NAD⁺, but NRC is more stable, cheaper, and has a clearer regulatory status in most regions. NRC also avoids the GI stability issues that plague some NMN formulations.
Nicotinamide Riboside Chloride Powder Mechanism of Action
NAD+ Precursor: Converts to nicotinamide mononucleotide (NMN) via nicotinamide riboside kinase (NRK1/2), then to NAD+ via NMN adenylyltransferase (NMNAT), bypassing rate-limiting steps of other B3 forms.
Sirtuin Activation: Elevated NAD+ activates SIRT1 (DNA repair, metabolism) and SIRT3 (mitochondrial function, antioxidant defense), reducing oxidative stress and enhancing cellular resilience.
Mitochondrial Enhancement: Boosts mitochondrial biogenesis, fatty acid oxidation, and glucose uptake, improving energy metabolism and insulin sensitivity.
Nicotinamide Riboside Chloride Powder Key Benefits & Applications
Anti-aging & Longevity: Slows NAD+ decline with age, supports DNA repair, and may extend healthspan in preclinical models.
Metabolic Health: Improves insulin sensitivity, reduces hepatic fat accumulation, and mitigates high-fat diet-induced metabolic dysfunction.
Neuroprotection: Enhances brain NAD+ levels, reduces cognitive decline in Alzheimer's models, and supports neuronal health.
Cardiovascular Support: Improves vascular function, reduces oxidative stress, and lowers heart disease risk factors.
Nicotinamide Riboside Chloride Powder Storage Requirements
Store in a cool, dry, and well-ventilated environment at 2–8℃.
Keep sealed to avoid exposure to moisture, light, and high temperatures.
Avoid contact with strong oxidants and acidic substances to prevent decomposition.
Comparison with Other NAD+ Precursors
| Precursor | Bioavailability | NAD+ Boost | Key Limitations |
|---|---|---|---|
| NRC | High (oral) | Moderate–high | Higher cost vs. nicotinamide |
| Nicotinamide | High | Low (feedback inhibition) | May suppress sirtuins at high doses |
| Nicotinic Acid | Moderate | Moderate | Flushing, GI upset |
| NMN | High | High | Variable stability; higher cost |
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Yinherb Lab founded in 2009, has been deeply committed to the biotechnology field for over a decade. Today, it has established a professional development framework integrating "R&D + production" as an integrated system. And always adhered to the core business philosophy of "Quality First, Service Second, Price Third".
Our address
No.3, Daqing rd, Hi-tech zone, Xi'an city, China.
Phone Number
+8618681897250
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