
Urolithin A 99% Powder CAS.1143-70-0 99%
English name: Urolithin A
CAS number: 1143-70-0
Molecular formula: C13H8O4
Molecular weight: 228.20000g/mol
EINECS number: 204-689-0
Capacity: 500kgs per month
Source: synthetic
Purity (HPLC) >99.0%
Place of Origin: China Yinherb-Lab
Packing: As per client's requirements
Minimum Order Quantity: 1kg
Storage: Store in cool & dry place, Keep away from strong light and heat for 2 years
Description
Xi’an Yinherb Bio-Tech Co., Ltd. is one of the leading manufacturers and suppliers of urolithin a 99% powder cas.1143-70-0 99% in China, also supports customized service. Welcome to buy bulk urolithin a 99% powder cas.1143-70-0 99% for sale here from our factory. Quality products and reasonable price are available.

Leading Research lab on Nutritional Supplements in China
Yinherb Lab is a professional research Lab in china, have focused on Nutritional Supplements, Nootropics and Peptide raw materials researching and producing in this market for over 10 years with stable quality and great reputations, we can supply every batch test, including COA, HPLC and NMR. I believe that we must work well in future.
Yinherb Lab High Quality Urolithin A 99% powder CAS.1143-70-0 99%
Chemical Name: 6-Hydroxy-2-(4-hydroxyphenyl)-benzofuran-3-one
CAS Number: 1143-70-0
Molecular Formula: C₁₃H₈O₄
Molecular Weight: 228.20
Appearance: Yellow to orange-yellow crystalline powder
Odor: Almost odorless
| Parameter | Specification |
|---|---|
| Solubility | Slightly soluble in cold water, readily soluble in dilute acids; water solubility increases with heating or ultrasonic treatment |
| Melting Point | >300°C (decomposes) |
| pH Value (1% Aqueous Solution) | 5.0-8.0 |
| Loss on Drying | ≤5.0% |
| Calcium Content | 21.0%-26.3% |
| Purity | ≥98.0% (HPLC) |
|
Application |
Anti-Aging and Enhancement of Cognitive Ability |
What is Urolithin A 99% powder?
Urolithin A is a natural product that can be obtained through the hydrolysis of tannins in fruits such as strawberries and pomegranates.
In recent years, urolithin A has been found to have multiple functions, including promoting the growth and metabolism of muscle cells, reducing oxidative stress, and alleviating inflammation, and has been proven to improve human health, especially the health of the elderly, and delay aging.
Related muscle degeneration and neurodegenerative diseases. Currently, this beneficial natural product has been further researched and developed. Through refined manufacturing and product positioning, urolithin A preparations can help consumers provide better health protection.
Urolithin A is also marketed as preparations for health foods, nutritional supplements and pharmaceuticals.

Urolithin A 99% powder Core Mechanisms of Action (Including 2025–2026 Discoveries)
1. Mitophagy Activation: Upregulates the PINK1/Parkin pathway to clear damaged mitochondria, promotes mitochondrial biogenesis, enhances energy metabolism and cellular vitality, and is the central mechanism for anti-aging effects.
2. Immune Rejuvenation: Induces metabolic remodeling of CD8+ T cells toward fatty acid oxidation, reduces exhaustion markers, enhances immune cell activity, and improves age-related immune decline (2026 Nature Aging clinical study).
3. Anti-inflammatory and Antioxidant Effects: Inhibits NF-κB and NLRP3 pathways, reduces IL-6 and TNF-α, scavenges ROS, and alleviates oxidative stress and tissue inflammation.
4. Metabolic and Signaling Regulation: Activates SIRT1/AMPK and inhibits PI3K/Akt/mTOR to regulate glucose and lipid metabolism and maintain autophagic balance.
5. Neuroprotection: Crosses the blood-brain barrier, inhibits Aβ deposition and excessive tau phosphorylation, and improves synaptic function and cognition.

Urolithin A 99% powder Key Application Areas (Research and Clinical Exploration)
1. Anti-aging and Metabolic Health
Muscle Function Improvement: Enhances endurance and reduces age-related muscle loss; human trials show a 42% improvement in endurance and a 65% increase in running capacity.
Immune Rejuvenation: Reverses age-related immune decline, increases naive T-cell numbers, and reduces T-cell exhaustion (2026 Phase I trial; 1000 mg/day for 4 weeks was safe).
Metabolic Regulation: Improves insulin sensitivity, aids blood glucose and weight management, and reduces fatty liver risk.
2. Neurodegenerative Diseases
Alzheimer's Disease: Reduces Aβ plaques and neuroinflammation and improves cognition and memory (animal models).
Parkinson's Disease / Stroke: Protects dopaminergic neurons, reduces ischemia-reperfusion injury, and promotes neural repair.
3. Sports Nutrition and Skin Health
Athletic Performance Enhancement: Boosts aerobic capacity and muscle endurance and accelerates recovery.
Skin Anti-aging: Activates mitophagy in skin cells, reduces UVB damage, and delays photoaging and intrinsic aging.
Cancer Adjuvant and Cardiovascular Protection
Cancer Inhibition: Induces autophagy and cell-cycle arrest in cancer cells, inhibits proliferation and migration, and may act as a chemo-/radio-sensitizer.
Cardiovascular Protection: Improves diabetic cardiomyopathy, reduces myocardial fibrosis, and protects vascular endothelium.
Comparison with Related Substances
| Substance | Source | Core Advantages | Typical Applications |
|---|---|---|---|
| Urolithin A | Gut metabolism / synthetic | Mitophagy activation + immune rejuvenation; high oral bioavailability | Anti-aging, sports nutrition, neuroprotection |
| Resveratrol | Grape skins / red wine | SIRT1 activation; anti-inflammatory and antioxidant | Cardiovascular health, metabolic regulation |
| Metformin | Synthetic drug | AMPK activation; glucose-lowering and weight management | Type 2 diabetes, metabolic syndrome |
Urolithin A 99% powder Test report - Yinherb Lab

Related products
Specized in Racetams, Sunifiram, Urolithin A/B, 9-Me-BC, Phenibut, L-Theanine, J-147, Noopept, phosphatidylserine, Alpha-GPC, CDP-Choline, etc.
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Yinherb Lab founded in 2009, has been deeply committed to the biotechnology field for over a decade. Today, it has established a professional development framework integrating "R&D + production" as an integrated system. And always adhered to the core business philosophy of "Quality First, Service Second, Price Third".
Our address
No.3, Daqing rd, Hi-tech zone, Xi'an city, China.
Phone Number
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