Lemairamin Powder CAS.29946-61-0 98% Min
English name: Lemairamin
CAS number: 29946-61-0
Molecular formula: C₁₉H₂₁NO₃
Molecular weight: 311.38g/mol
Capacity: 50kgs per month
Source: synthetic
Purity (HPLC) >99.0%
Place of Origin: China Yinherb-Lab
Packing: As per client's requirements
Minimum Order Quantity: 1kg
Storage: Store in cool & dry place, Keep away from strong light and heat for 2 years
Description
Xi’an Yinherb Bio-Tech Co., Ltd. is one of the leading manufacturers and suppliers of lemairamin powder cas.29946-61-0 98% min in China, also supports customized service. Welcome to buy bulk lemairamin powder cas.29946-61-0 98% min for sale here from our factory. Quality products and reasonable price are available.

Leading Research lab on Nutritional Supplements in China
Yinherb Lab is a professional research Lab in china, have focused on Nutritional Supplements, Nootropics and Peptide raw materials researching and producing in this market for over 10 years with stable quality and great reputations, we can supply every batch test, including COA, HPLC and NMR. I believe that we must work well in future.
Yinherb Lab High Quality Lemairamin Powder (WGX-50) CAS.29946-61-0 98% Min
Product Identification
| English name | Lemairamin Powder (WGX-50) |
| Chemical Formula | C₁₉H₂₁NO₃ |
| Molecular Weight | 311.38 |
| CAS Number | 29946-61-0 |
| Appearance | It presents as an off-white powder. |
| Purity | Commercially available products usually have a purity of over 99%, for example, the purity of the product numbered HY - 112584 on MedChemExpress reaches 99.94%. |
| Storage Requirement | It should be stored in a tightly sealed container in a cool, dry and dark environment, and freezing storage at -20°C is recommended. |
Core Characteristics
Source & Structure: Derived from the pericarps of Zanthoxylum plants, it can also be artificially synthesized. Its chemical name is N-[2-(3,4-dimethoxyphenyl)-ethyl]-3-phenylacrylamide.
Physical Properties: Typically appears as a white crystalline powder with a purity of 98%-99%. It requires storage in a cool and dry environment to maintain stability.
Target Receptor: Acts as a selective agonist of the α7 nicotinic acetylcholine receptor (α7nAChR), exerting various biological effects through activating this receptor.
What is Lemairamin Powder (WGX-50)?
Lemairamin Powder (WGX-50, CAS 29946-61-0, ≥98% HPLC) is a natural alkaloid purified from Zanthoxylum bungeanum. As a selective α7nAChR agonist, it exerts potent neuroprotection, anti-neuroinflammation, and cognitive enhancement in preclinical studies. Widely used in nootropic research, anti-Alzheimer's drug discovery, anti-aging cosmetics, and brain health supplements. High purity, stable quality, and versatile solubility make it a premium raw material for neuroscience research and functional product development.
Core Features
High-purity natural alkaloid from Zanthoxylum bungeanum (Sichuan pepper) with defined α7nAChR agonist activity.
Demonstrates dual neuroprotective/anti-inflammatory effects, targeting both cognitive decline and neuroinflammation.
High purity (≥98–99%) ensures low impurities and reliable batch-to-batch consistency.
Good solubility in organic solvents facilitates formulation in research, cosmetics, and supplements.


Lemairamin Powder (WGX-50) Benefits and Functions
Neuroprotection & Anti-dementia: Inhibits β-amyloid (Aβ)-induced neuronal apoptosis, reduces neuronal calcium toxicity, and decreases Aβ oligomer accumulation in the cerebral cortex. It improves cognitive function in model animals and alleviates Alzheimer's disease-related pathological processes by suppressing neuroinflammation.
Analgesic Effect: After activating α7nAChR, it reduces pain hypersensitivity via the spinal IL-10/β-endorphin pathway. It effectively inhibits chronic pain such as formalin-induced tonic pain and bone cancer pain, but shows no significant effect on acute pain.
Other Potential Efficacies: Possesses anti-inflammatory and antioxidant properties, which may help reduce wrinkles and enhance skin elasticity in skincare applications. Preliminary studies also suggest potential antibacterial and digestive regulatory effects.

Lemairamin Powder (WGX-50) Application
Laboratory Research: Tool compound for α7nAChR-related studies, neurodegenerative disease research (Alzheimer's disease), chronic pain mechanism studies.
Dietary Supplements: Raw material for cognitive support, anti-inflammatory, or pain management supplements (for research-use-only formulations; human consumption requires regulatory approval).
Cosmetics: Ingredient in natural anti-aging skincare products (serums, creams) to improve skin firmness and reduce oxidative damage.
FAQ
| Question | Answer |
|---|---|
| Source | Natural extraction from Zanthoxylum bungeanum pericarp |
| Core Advantage | Selective α7nAChR agonist with neuroprotection & anti-inflammation |
| MOQ & Sample | 10–50 g samples available; bulk supply (kg–ton) supported |
| Supporting Documents | COA, HPLC, LC-MS, NMR, MSDS, and full qualification docs |
| Shelf Life | 24 months sealed, cool/dry/light-shielded |
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Yinherb Lab founded in 2009, has been deeply committed to the biotechnology field for over a decade. Today, it has established a professional development framework integrating "R&D + production" as an integrated system. And always adhered to the core business philosophy of "Quality First, Service Second, Price Third".
Our address
No.3, Daqing rd, Hi-tech zone, Xi'an city, China.
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