JBSNF-000088 Powder CAS.7150-23-4 99% Min
English name: JBSNF-000088
CAS number: 7150-23-4
Molecular formula: C₇H₈N₂O₂O
Molecular weight: 152.15g/mol
Capacity: 50kgs per month
Source: synthetic
Purity (HPLC) >99.0%
Place of Origin: China Yinherb-Lab
Packing: As per client's requirements
Minimum Order Quantity: 1kg
Storage: Store in cool & dry place, Keep away from strong light and heat for 2 years
Description
Xi’an Yinherb Bio-Tech Co., Ltd. is one of the leading manufacturers and suppliers of jbsnf-000088 powder cas.7150-23-4 99% min in China, also supports customized service. Welcome to buy bulk jbsnf-000088 powder cas.7150-23-4 99% min for sale here from our factory. Quality products and reasonable price are available.
Leading Research lab on Nutritional Supplements in China
Yinherb Lab is a professional research Lab in china, have focused on Nutritional Supplements, Nootropics and Peptide raw materials researching and producing in this market for over 10 years with stable quality and great reputations, we can supply every batch test, including COA, HPLC and NMR. I believe that we must work well in future.
Yinherb Lab High Quality JBSNF-000088 powder CAS.7150-23-4 99% Min
Product Identification
| English name | JBSNF-000088 |
| Chemical Formula | C₇H₈N₂O₂ |
| Molecular Weight | 152.15 |
| CAS Number | 7150 - 23 - 4 |
| Appearance | It presents as an off-white powder. |
| Purity | Commercially available products usually have a purity of over 99%, for example, the purity of the product numbered HY - 112584 on MedChemExpress reaches 99.94%. |
| Storage Requirement | It should be stored in a tightly sealed container in a cool, dry and dark environment, and freezing storage at -20°C is recommended. |
What is JBSNF-000088 powder?
JBSNF-000088 (6-Methoxynicotinamide) is a highly potent, orally active NNMT inhibitor for metabolic disorder research. By targeting NNMT, it reduces MNA levels, enhances insulin sensitivity, promotes fat loss, and improves glucose and lipid homeostasis. Ideal for obesity, type 2 diabetes, and NAFLD studies, it serves as a critical tool compound for exploring NNMT as a therapeutic target.
Core Advantages
High Potency & Selectivity: Low IC₅₀ against human NNMT; minimal off-target effects.
Oral Bioavailability: Effective via oral administration, suitable for long-term in vivo studies.
Proven Efficacy: Reduces body weight, improves glycemic control, and normalizes lipid profiles in preclinical models.
Low Toxicity: Well-tolerated in animal studies with no observed severe adverse effects.
Stable & Easy to Handle: Crystalline powder with good stability; straightforward storage and solution preparation.
JBSNF-000088 powder Benefits and Functions
Potent NNMT Inhibitor: Selectively inhibits Nicotinamide N-Methyltransferase (NNMT) with IC₅₀ = 1.8 μM (human), 2.8 μM (monkey), 5.0 μM (mouse).
Reduces MNA Levels: Blocks NNMT-catalyzed methylation of nicotinamide, lowering 1-methylnicotinamide (MNA) in adipose and liver tissue.
Improves Insulin Sensitivity: Enhances glucose uptake and utilization, improving oral glucose tolerance in obesity and diabetes models.
Regulates Lipid Metabolism: Reduces visceral fat mass, plasma/liver triglycerides, and body weight in diet-induced obesity (DIO) mice.
Modulates Energy Homeostasis: Shifts metabolism toward fat oxidation, increases energy expenditure without affecting appetite.
JBSNF-000088 powder Application
Metabolic Disease Research: Obesity, type 2 diabetes, non-alcoholic fatty liver disease (NAFLD) studies.
Insulin Resistance Research: Mechanistic studies and drug development for insulin sensitization.
Adipose Tissue Biology: White adipose tissue (WAT) function, browning, and lipid metabolism research.
NNMT Pathway Studies: Target validation and pharmacological tool for NNMT-mediated metabolic regulation.
JBSNF-000088 powder Quality Control (QC)
| Test Item | Method | Standard |
|---|---|---|
| Purity | HPLC/LC-MS | ≥98.0% / ≥99.0% |
| Identity | ¹H-NMR, LC-MS | Matches reference standard |
| Loss on Drying | Karl Fischer | ≤0.5% |
| Related Substances | HPLC | Total impurities ≤1.0% |
| Heavy Metals | ICP-MS | Meet research-grade safety requirements |
FAQ
Dissolution: Prepare stock solutions in DMSO (2 mg/mL); dilute with aqueous buffer for in vitro/in vivo use.
Dosage Reference: In vivo: 50 mg/kg (oral, 4 weeks) in DIO mice; In vitro: 1–10 μM for cell-based assays.
Documents: COA, HPLC, LC-MS, NMR, and MSDS available.
Packaging: 1 g, 5 g, 25 g, 100 g; custom packaging supported.
Shipping: Room temperature (powder); cold chain for bulk orders.
Related products
Specized in 5A-Hydroxy Laxogenin, 6-Paradol, 5-Amino-1-Mq, JBSNF-000088, BAM-15, SLU-PP-332, Urolithin A/B, 9-Me-BC, Noopept, phosphatidylserine, Alpha-GPC, CDP-Choline, etc.
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Yinherb Lab founded in 2009, has been deeply committed to the biotechnology field for over a decade. Today, it has established a professional development framework integrating "R&D + production" as an integrated system. And always adhered to the core business philosophy of "Quality First, Service Second, Price Third".
Our address
No.3, Daqing rd, Hi-tech zone, Xi'an city, China.
Phone Number
+8618681897250
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