Acacetin Powder CAS.480-44-4 98% Min
English name: Acacetin
CAS number: 480-44-4
Molecular formula: C₁₆H₁₂O₅
Molecular weight: 284.26g/mol
Capacity: 50kgs per month
Source: synthetic
Purity (HPLC) >99.0%
Place of Origin: China Yinherb-Lab
Packing: As per client's requirements
Minimum Order Quantity: 1kg
Storage: Store in cool & dry place, Keep away from strong light and heat for 2 years
Description
Xi’an Yinherb Bio-Tech Co., Ltd. is one of the leading manufacturers and suppliers of acacetin powder cas.480-44-4 98% min in China, also supports customized service. Welcome to buy bulk acacetin powder cas.480-44-4 98% min for sale here from our factory. Quality products and reasonable price are available.
Leading Research lab on Nutritional Supplements in China
Yinherb Lab is a professional research Lab in china, have focused on Nutritional Supplements, Nootropics and Peptide raw materials researching and producing in this market for over 10 years with stable quality and great reputations, we can supply every batch test, including COA, HPLC and NMR. I believe that we must work well in future.
Yinherb Lab High Quality Acacetin Powder CAS.480-44-4 98% Min
Product Identification
| English name | Acacetin Powder |
| Chemical Name | 5,7-Dihydroxy-4'-methoxyflavone |
| Chemical Formula | C₁₆H₁₂O₅ |
| Molecular Weight | 284.26 |
| CAS Number | 480-44-4 |
| Appearance | Light yellow to off-white crystalline powder |
| Purity | Commercial grades typically ≥98% (HPLC-verified), with low impurities (heavy metals ≤10 ppm, moisture ≤0.5%) |
| Solubility | Soluble in DMSO, ethanol, and methanol; slightly soluble in water; insoluble in non-polar organic solvents (e.g., hexane, chloroform) |
| Storage Requirement | Store in a cool, dry, and light-protected environment (2–8 °C recommended for long-term stability). Avoid exposure to direct sunlight, heat, and moisture. |
| Acacetin is predominantly isolated from plant materials |
Chrysanthemum morifolium (common chrysanthemum): A major source, used in traditional Chinese medicine for its anti-inflammatory properties. Scutellaria baicalensis (skullcap): A medicinal herb rich in flavonoids, including acacetin. Apium graveolens (celery): Contains trace amounts in seeds and leaves. Other sources: Chamomile, honeysuckle, and certain citrus fruits. |
What is Acacetin Powder?
Acacetin Powder (CAS 480-44-4, ≥98% HPLC) is a natural flavonoid extracted and purified from various plants. It possesses outstanding antioxidant, anti-inflammatory, whitening and antibacterial biological activities. It is widely used in high-end whitening skincare raw materials, antioxidant health products, as well as inflammation-related and antiviral pharmaceutical research fields. With stable efficacy and high application value, it is a popular natural functional raw material in cosmetic and health industry.
Core Features
High purity natural flavonoid compound with stable chemical structure and stable batch quality.
It owns excellent antioxidant and anti-inflammatory properties, and has remarkable effects on inhibiting melanin formation.
With good solubility in common organic solvents, it is easy to be formulated into various skincare and health products.
Featuring mild activity and high safety, it can be widely matched with other plant extracts and functional raw materials for multi-effect formula development.
Acacetin Powder Benefits and Functions
Acacetin exhibits a range of pharmacologically relevant activities, supported by preclinical research:
Anti-Inflammatory Effects: Inhibits pro-inflammatory cytokines (TNF-α, IL-6, IL-1β) and suppresses the NF-κB signaling pathway, alleviating acute and chronic inflammation (e.g., in arthritis, respiratory inflammation models).
Antioxidant Activity: Scavenges free radicals (superoxide anions, hydroxyl radicals) and enhances endogenous antioxidant enzyme activity (SOD, GSH-Px), reducing oxidative stress-induced cell damage.
Neuroprotective Properties: Crosses the blood-brain barrier, protects neurons from oxidative damage and neuroinflammation, and may reduce amyloid-beta (Aβ) aggregation-showing potential for Alzheimer's disease research.
Cardioprotective Effects: Improves vascular endothelial function, inhibits platelet aggregation, and reduces lipid peroxidation, supporting cardiovascular health in preclinical models.
Anticancer Potential: Induces apoptosis in various cancer cell lines (e.g., breast, lung, colon cancer) by regulating cell cycle progression and suppressing oncogenic signaling pathways (e.g., PI3K/Akt), with low toxicity to normal cells.
Antimicrobial Activity: Exhibits inhibitory effects against pathogenic bacteria (e.g., Staphylococcus aureus, Escherichia coli) and fungi (e.g., Candida albicans), primarily by disrupting microbial cell membranes.
Acacetin Powder Application
Biomedical Research: A valuable tool compound for studying flavonoid biology, inflammation, neurodegeneration, and cancer mechanisms.
Dietary Supplements: Used as a natural bioactive ingredient in supplements targeting immune support, anti-inflammation, and cardiovascular health (formulated as capsules, tablets, or liquid extracts).
Cosmetics: Incorporated into skincare products (serums, creams) for its antioxidant and anti-inflammatory properties, helping to soothe irritated skin, reduce oxidative aging, and improve skin barrier function.
Pharmaceutical Development: Investigated as a lead compound for developing therapies for inflammatory diseases, neurodegenerative disorders, and certain cancers.
Quality Control
| Test Item | Method | Standard |
|---|---|---|
| Purity | HPLC | ≥98.0% / ≥99.0% |
| Identity | LC-MS / NMR / FT-IR | Matches reference standard |
| Loss on Drying | Karl Fischer | ≤0.5% |
| Related Substances | HPLC | Total impurities ≤1.0% |
| Heavy Metals | ICP-MS | Compliant with cosmetic and food safety limits |
FAQ
| Question | Answer |
|---|---|
| Water Solubility | Slightly soluble in water, easy to dissolve in ethanol and DMSO |
| Core Advantage | Natural flavone with dual effects of brightening, anti-oxidation and anti-inflammation |
| MOQ & Sample | 10g–50g test samples available; bulk large quantity supply supported |
| Supporting Documents | COA, HPLC, LC-MS, NMR, MSDS complete qualification documents |
| Shelf Life | 24 months under sealed, cool dry and light-shielded environment |
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Yinherb Lab founded in 2009, has been deeply committed to the biotechnology field for over a decade. Today, it has established a professional development framework integrating "R&D + production" as an integrated system. And always adhered to the core business philosophy of "Quality First, Service Second, Price Third".
Our address
No.3, Daqing rd, Hi-tech zone, Xi'an city, China.
Phone Number
+8618681897250
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