Hexapeptide-9 powder CAS. 1228371-11-6 99% Purity Min
English Name:Hexapeptide-9
CAS No.: 1228371-11-6
Molecular Weight:~793.0 g/mol (unmodified); ~921.2 g/mol (palmitoyl-modified)
Molecular Formula:C₃₆H₆₈N₁₀O₈ (unmodified form); C₄₄H₈₄N₁₀O₉ (palmitoyl-modified form)
Appearance:White powder
Odor: no
Stability: stable
MSDS and COA: available for your reference
Capacity: 500g per month
Appearance: white powder
Source: synthetic
Purity (HPLC) >98.0%
Place of Origin: China Yinherb-Lab
Packing: As per client's requirements
Minimum Order Quantity: 10g
Storage: Store in cool & dry place, Keep away from strong light and heat for 2 years
Description
Xi’an Yinherb Bio-Tech Co., Ltd. is one of the leading manufacturers and suppliers of Hexapeptide-9 powder CAS. 1228371-11-6 99% Purity Min in China, also supports customized service. Welcome to buy bulk Hexapeptide-9 powder CAS. 1228371-11-6 99% Purity Min for sale here from our factory. Quality products and reasonable price are available.

Leading Research lab on Nootropics & peptide in China
Yinherb Lab is a professional research Lab in china, have focused on Nutritional Supplements, Nootropics and Peptide raw materials researching and producing in this market for over 10 years with stable quality and great reputations, we can supply every batch test, including COA, HPLC and NMR. I believe that we must work well in future.
Yinherb Lab High Quality Hexapeptide-9 Powder CAS. 1228371-11-6 99% Purity Min
| Category | Details |
|---|---|
| Chemical name | Hexapeptide-9 |
| INCI name | Oligopeptide-11, Palmitoyl Hexapeptide-9 (sometimes with palmitoyl modification for enhanced absorption) |
| Chemical Formula | C₃₆H₆₈N₁₀O₈ (unmodified form); C₄₄H₈₄N₁₀O₉ (palmitoyl-modified form) |
| Molecular Weight | ~793.0 g/mol (unmodified); ~921.2 g/mol (palmitoyl-modified) |
| CAS Number | 1228371-11-6 |
| Appearance | White to off-white crystalline powder or lyophilized solid |
| Amino Acid Sequence | Lys-Val-Lys-Leu-Val-Leu (K-V-K-L-V-L, N-terminal to C-terminal) |
| Solubility | Water-soluble (≥50 mg/mL in deionized water), slightly soluble in glycerol, insoluble in oils and non-polar solvents |
| Stability | Stable under neutral pH (5.5–7.5); prone to degradation under strong acid (pH <4) or alkali (pH >8), and high temperature (>50℃) |
| Shelf Life | Seal tightly, store at 2–8℃ in a cool, dry, dark environment; avoid moisture and repeated freezing-thawing (solid shelf life: 2 years; dissolved solution: 1–2 weeks when refrigerated) |
What is Hexapeptide-9 Powder?
Hexapeptide‑9 Powder (CAS 122039‑38‑5, ≥98% HPLC) is a premium anti‑aging cosmetic peptide that strongly promotes collagen synthesis, improves skin elasticity, and reduces fine lines and sagging. With high water solubility and excellent stability, it is widely used in high‑end serums, firming creams, and repair skincare formulas. Our high‑purity lyophilized grade ensures consistent performance and easy formulation - trusted by global skincare brands for professional anti‑aging solutions.
High purity ≥98% (HPLC verified)
Excellent water solubility for easy formulation
Strong collagen‑boosting & firming effect
Stable lyophilized peptide grade
Ideal for anti‑aging, firming, and wrinkle‑care products


Hexapeptide-9 Powder Mechanism of Action
Core Mechanism of Action
Promotes Collagen & Elastin Synthesis: Stimulates dermal fibroblasts to produce collagen (types I, III) and elastin, enhancing skin's structural support and reducing fine lines/wrinkles.
Repairs Skin Barrier: Boosts synthesis of filaggrin and ceramides, strengthening the stratum corneum's moisture-locking ability and improving dry, sensitive skin.
Inhibits Matrix Metalloproteinases (MMPs): Reduces MMP activity to prevent collagen degradation caused by aging and environmental stress (e.g., UV rays), slowing skin sagging.
Main Efficacy
Anti-aging & Firming: Tightens facial contours, fades static wrinkles (e.g., nasolabial folds) and dynamic fine lines, making skin more elastic.
Barrier Repair: Relieves dryness, roughness, and redness, suitable for damaged or sensitive skin.
Improves Skin Texture: Enhances skin's smoothness and luster by regulating cellular metabolism and promoting healthy skin cell turnover.

Hexapeptide-9 Powder Application
Application Field: Primarily used in anti-aging, firming, and barrier-repair skin care products.
Common Product Types: Serums/essences (recommended concentration: 0.001%–0.005%), day/night creams (0.0005%–0.003%), eye creams (0.0005%–0.002%), and repair masks (0.002%–0.004%).
Formulation Compatibility: Works well with hyaluronic acid, niacinamide, other peptides (e.g., Acetyl Hexapeptide-8), and plant extracts (e.g., centella asiatica); avoid mixing with high-concentration alcohol (>20%) or oxidants.
Quality Control
| QC Item | Method | Standard |
|---|---|---|
| Purity | HPLC | ≥98.0% |
| Identity | LC‑MS | Conforms |
| Moisture | Karl Fischer | ≤5.0% |
| Acetate Content | Ion Chromatography | ≤8.0% |
| Heavy Metals (Pb/Cd/As/Hg) | AAS | Complies with limits |
| Total Aerobic Count | USP | ≤100 CFU/g |
| Salmonella / E. coli | USP | Negative |
FAQ
| Question | Answer |
|---|---|
| Q1: Is Hexapeptide‑9 soluble in water? | A1: Yes, highly soluble in water and aqueous cosmetic bases. |
| Q2: What skincare products is it used in? | A2: Serums, creams, masks, ampoules - mainly anti‑aging & firming lines. |
| Q3: What is the MOQ? | A3: MOQ: 1 gram. Lab packs & bulk orders available. |
| Q4: Do you provide COA & MSDS? | A4: Yes, COA, MSDS, and HPLC/LCMS data are provided per batch. |
| Q5: How to store? | A5: Store at -20°C for long‑term stability; avoid repeated freeze‑thaw. |
| Q6: Can I get a sample? | A6: Yes, small samples available for R&D testing. |
Hexapeptide‑9 vs Hexapeptide‑8 vs Acetyl Hexapeptide‑8 (Argireline) comparation
| Aspect | Hexapeptide‑9 | Hexapeptide‑8 | Acetyl Hexapeptide‑8 (Argireline) |
|---|---|---|---|
| CAS | 122039‑38‑5 | 146438‑70‑2 | 616204‑22‑9 |
| Type | Collagen‑stimulating peptide | Collagen & repair peptide | Anti‑wrinkle neuropeptide |
| Core Mechanism | Boosts collagen I & III, firms skin | Promotes collagen, repairs skin | Relaxes facial muscles, reduces expression lines |
| Main Function | Anti‑aging, firming, lifting, anti‑sagging | Anti‑aging, repair, elasticity | Anti‑wrinkle (forehead, eye area), expression line reduction |
| Best For | Firming, lifting, anti‑sagging products | Repair, elasticity, rejuvenation | Wrinkle reduction, Botox‑like effect |
| Purity | ≥98% HPLC | ≥98% HPLC | ≥98% HPLC |
| Solubility | High water solubility | High water solubility | High water solubility |
| Storage | -20°C, sealed, dry | -20°C, sealed, dry | -20°C, sealed, dry |
| Applications | Serums, creams, masks, anti‑aging | Repair serums, anti‑aging creams | Eye creams, wrinkle serums, ampoules |
| Unique Advantage | Best for firmness & density | Best for dermal repair | Best for dynamic expression lines |
Related products
Specized in Nonapeptide-1, Acetyl Hexapeptide 38, Oligopeptide-1, Acetyl Hexapeptide-37, Acetyl Octapeptide 3, Matrixyl 3000, Blue Copper Peptide Powder and son on.
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Yinherb Lab founded in 2009, has been deeply committed to the biotechnology field for over a decade. Today, it has established a professional development framework integrating "R&D + production" as an integrated system. And always adhered to the core business philosophy of "Quality First, Service Second, Price Third".
Our address
No.3, Daqing rd, Hi-tech zone, Xi'an city, China.
Phone Number
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