Oligopeptide P11-4 Powder CAS. 593266-60-5 99% Purity Min
English Name:Oligopeptide P11-4 powder
CAS No.: 593266-60-5
Molecular Weight:1595.67g/mol
Molecular Formula:C₇₂H₉₉N₂₀O₂₂
Appearance:White powder
Odor: no
Stability: stable
MSDS and COA: available for your reference
Capacity: 500g per month
Appearance: white powder
Source: synthetic
Purity (HPLC) >98.0%
Place of Origin: China Yinherb-Lab
Packing: As per client's requirements
Minimum Order Quantity: 10g
Storage: Store in cool & dry place, Keep away from strong light and heat for 2 years
Description
Xi’an Yinherb Bio-Tech Co., Ltd. is one of the leading manufacturers and suppliers of oligopeptide p11-4 powder cas. 593266-60-5 99% purity min in China, also supports customized service. Welcome to buy bulk oligopeptide p11-4 powder cas. 593266-60-5 99% purity min for sale here from our factory. Quality products and reasonable price are available.

Leading Research lab on Nootropics & peptide in China
Yinherb Lab is a professional research Lab in china, have focused on Nutritional Supplements, Nootropics and Peptide raw materials researching and producing in this market for over 10 years with stable quality and great reputations, we can supply every batch test, including COA, HPLC and NMR. I believe that we must work well in future.
Yinherb Lab High Quality Oligopeptide P11-4 powder CAS. 593266-60-5 99% Purity Min
Generic Name: Oligopeptide P11-4 powder
INCI name: Oligopeptide 104
CAS Number: 1415456-99-3
Molecular Formula: C₇₂H₉₉N₂₀O₂₂
Molecular Weight: 1595.67 Da (exact calculated value)
Chemical Classification: Synthetic sugar derivative (xylose-based tetrahydropyran ring derivative)
Amino Squence: Ac - Gln - Gln - Arg - Phe - Glu - Trp - Glu - Phe - Glu - Gln - Gln - NH₂ (abbreviated as Ac - QQRFEWEFEQQ - NH₂)
Appearance: It is a white to off-white solid powder.
Solubility: It has a solubility of 16.67 mg/mL in DMSO, and ultrasonic treatment can assist in dissolving it. The quality of products on the market is relatively stable, with a common purity specification of 98.02%.
Stability: Excellent stability within the pH range of 3.0–8.0 (compatible with most skincare formulations), heat-resistant (no decomposition under short-term heating at ≤80℃), non-oxidizable, and well-compatible with other active skincare ingredients (e.g., vitamin C, hyaluronic acid).
Purity Requirement: Common specifications include 98% and 99%, and some high-end products can even reach 99.67% purity. The total impurity content is generally ≤2.0%, and the largest single impurity is ≤1.0%, which meets the strict requirements of pharmaceutical research.
What is Oligopeptide P11-4 powder?
Oligopeptide P11-4 Powder (CAS 593266-60-5, ≥98% HPLC) is a synthetic pH-sensitive self-assembling peptide composed of 11 amino acids. Developed for biomimetic enamel regeneration, it selectively forms a 3D hydrogel matrix in acidic oral environments, acting as a scaffold for hydroxyapatite nucleation and growth. It effectively repairs demineralized enamel, reduces dental sensitivity, and prevents plaque formation. Ideal for high-end oral care products and professional dental treatments, it offers a safe, non-invasive alternative to fluoride and abrasive agents.
Core Features
pH-responsive self-assembling peptide with enamel-targeted biomineralization activity;
forms protective 3D matrix only at acidic pH (caries/plaque sites);
high affinity to tooth mineral, guiding natural-like hydroxyapatite growth;
non-invasive, no fluoride or abrasives;
biocompatible, low immunogenicity;
stable in formulation, compatible with common oral care ingredients.


Oligopeptide P11-4 powder Mechanism of Action and Additional Efficacy
| Mechanism | Description |
|---|---|
| pH-Responsive Self-Assembly | Low pH triggers folding into β-sheet 3D hydrogel matrix |
| Hydroxyapatite Nucleation | Matrix provides Ca²⁺ binding sites, mimicking tooth mineral lattice |
| Enamel Remineralization | Guides new hydroxyapatite crystal growth, repairing demineralized enamel |
| Plaque & Sensitivity Control | Blocks bacterial adhesion; occludes dentinal tubules, reducing sensitivity |
| Biomimetic Mineralization | Matches natural enamel regeneration pathway, no harsh abrasives |

Oligopeptide P11-4 powder Application
Enamel regeneration and early caries treatment: It is one of its core applications. For early caries lesions that have not yet damaged the deep tooth tissue, the powder can be used as an active ingredient to prepare relevant preparations. These preparations can promote the remineralization of decayed tooth surfaces and reverse early tooth demineralization. Meanwhile, it can help regenerate damaged enamel, improving the hardness and integrity of teeth.
Relief of dentin hypersensitivity: Dentin hypersensitivity is often caused by the exposure of dentin tubules. The hydrogel-like structure formed by the self-assembly of this peptide powder can block the exposed dentin tubules. This reduces the stimulation of external substances on the dental nerve, thereby alleviating the sensitive symptoms such as soreness caused by cold, heat, acid, and sweetness.
Oral acid protection and care products: It can be added to oral care products such as toothpaste, mouthwash, and dental gels as an active ingredient. It can form a protective film on the tooth surface, enhance the tooth's resistance to acid erosion, and prevent enamel demineralization caused by acidic substances in food or beverages.
Quality Control (QC)
| Test Item | Method | Standard |
|---|---|---|
| Purity | HPLC | ≥98.0% / ≥99.0% |
| Identity | LC-MS, NMR, FT-IR | Matches reference standard |
| Sequence Confirmation | Peptide sequencing | Correct amino acid sequence |
| Loss on Drying | Karl Fischer | ≤0.5% |
| Heavy Metals | ICP-MS | Pb < 10 ppm; As < 2 ppm |
| Related Substances | HPLC | Total impurities ≤1.0% |
FAQ
| Question | Answer |
|---|---|
| Recommended Dosage | 0.1%–1.0% in toothpaste; 2%–5% in professional gels |
| pH Range for Activity | Optimal: pH 4.0–5.5; inactive at neutral pH (>6.5) |
| Shelf Life | 24 months sealed at -20°C; 12 months at 2–8°C |
| MOQ & Sample | 1 g MOQ; 10–50 mg research samples available |
| Certifications | GMP, ISO 22716; DMF filing available |
| Shipping | Room temperature; avoid extreme heat/moisture |
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Yinherb Lab founded in 2009, has been deeply committed to the biotechnology field for over a decade. Today, it has established a professional development framework integrating "R&D + production" as an integrated system. And always adhered to the core business philosophy of "Quality First, Service Second, Price Third".
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