Evodiamine Powder CAS.518-17-2 98% Min
English name: Evodiamine
CAS number: 518-17-2
Molecular formula: C₁₉H₁₇N₃O
Molecular weight: 303.36g/mol
Capacity: 50kgs per month
Source: synthetic
Purity (HPLC) >99.0%
Place of Origin: China Yinherb-Lab
Packing: As per client's requirements
Minimum Order Quantity: 1kg
Storage: Store in cool & dry place, Keep away from strong light and heat for 2 years
Description
Xi’an Yinherb Bio-Tech Co., Ltd. is one of the leading manufacturers and suppliers of evodiamine powder cas.518-17-2 98% min in China, also supports customized service. Welcome to buy bulk evodiamine powder cas.518-17-2 98% min for sale here from our factory. Quality products and reasonable price are available.
Leading Research lab on Nutritional Supplements in China
Yinherb Lab is a professional research Lab in china, have focused on Nutritional Supplements, Nootropics and Peptide raw materials researching and producing in this market for over 10 years with stable quality and great reputations, we can supply every batch test, including COA, HPLC and NMR. I believe that we must work well in future.
Yinherb Lab High Quality Evodiamine powder CAS.518-17-2 98% Min
Product Identification
| Product Name | Evodiamine | - |
| CAS Number | 518-17-2 | - |
| EC Number | 208-248-8 | - |
| Chemical Formula | C₁₉H₁₇N₃O | Elemental Analysis |
| Molecular Weight | 303.36 g/mol | Theoretical Calculation |
| Purity (HPLC) | ≥98% (Pharmaceutical Grade); ≥95% (Cosmetic/Dietary Supplement Grade) | HPLC (GB/T 22258-2018; USP 45-NF 40) |
| Appearance | Pale yellow needle-like crystals; odorless | Visual & Olfactory Inspection |
| Melting Point | 278 - 282°C (decomposition point excluded) | Differential Scanning Calorimetry (DSC) |
| Solubility | Slightly soluble in water (<0.1 g/100 mL, 25°C); soluble in ethanol (≥10 g/100 mL), methanol (≥12 g/100 mL), chloroform (≥15 g/100 mL) | Gravimetric Method |
| Loss on Drying | ≤1.0% | Vacuum Drying at 105°C for 2h (USP <731>) |
| Residue on Ignition | ≤0.5% | Ashing at 600°C (EP 2.4.16) |
| Heavy Metals | Total heavy metals ≤10 ppm; Lead (Pb) ≤2 ppm; Cadmium (Cd) ≤0.5 ppm | Inductively Coupled Plasma Mass Spectrometry (ICP-MS) |
| Microbial Limits | Total Aerobic Microbial Count ≤100 CFU/g; Yeast & Mold ≤10 CFU/g; Pathogens (E. coli, Salmonella) Negative | USP <61> & <62> |
| Storage Conditions | Store in a sealed container, protected from light, heat, and moisture; store at 2 - 8°C for long-term preservation (≥24 months shelf life) | Stability Test (ICH Q1A) |
What is Evodiamine powder ?
Evodiamine Powder is a high purity natural plant alkaloid active ingredient. It possesses fat burning, anti-inflammatory, analgesic and anti-proliferation effects. Mainly used in weight management research, pharmaceutical development and botanical functional product formulation.
Core Features
Natural alkaloid extracted from evodia rutaecarpa, owns multiple pharmacological activities.
Stable chemical property and distinct bioactivity.
Widely applied in fat metabolism, anti-inflammation and antitumor research fields.
Good compatibility with herbal extracts, suitable for various formula research.
Evodiamine powder Benefits and Functions
Anti-tumor Effects: It exhibits inhibitory activity against various cancer cell lines (e.g., lung, breast, colon, and liver cancer) by inducing cell cycle arrest, promoting apoptosis, and suppressing angiogenesis and metastasis.
Anti-inflammatory Action: It regulates pro-inflammatory cytokines (e.g., TNF-α, IL-6) and inhibits the NF-κB signaling pathway, showing potential in alleviating inflammatory disorders.
Metabolic Regulation: Studies suggest it may enhance thermogenesis, improve insulin sensitivity, and reduce obesity-related lipid accumulation, making it a research target for metabolic syndrome.
Neurological Effects: It interacts with TRPV1 receptors and exhibits neuroprotective properties, with preliminary research exploring its potential in treating neurodegenerative diseases.
Evodiamine powder Application
1.1 Pharmaceutical Field
Anti-tumor Drug R&D: Serves as a lead compound for developing targeted anti-cancer drugs. Its mechanism of inducing cancer cell apoptosis and inhibiting angiogenesis is widely studied in preclinical research, with potential applications in the treatment of non-small cell lung cancer, breast cancer, and colorectal cancer.
Anti-inflammatory & Analgesic Agents: Used in the development of drugs for treating chronic inflammatory diseases (e.g., rheumatoid arthritis, inflammatory bowel disease) by regulating the NF-κB signaling pathway and reducing the release of pro-inflammatory cytokines.
Metabolic Disease Therapeutics: A promising candidate for anti-obesity and anti-diabetic drug development, as it enhances energy metabolism, improves insulin resistance, and reduces visceral fat accumulation through activating TRPV1 receptors.
1.2 Cosmetic Field
Anti-aging & Skin Firming Products: Added to serums, creams, and lotions for its antioxidant properties, which scavenge free radicals, reduce oxidative stress on skin cells, and delay collagen degradation, thereby improving skin elasticity and reducing fine lines.
Oil-Control & Acne-Reducing Formulations: Regulates sebum gland secretion and exerts mild antibacterial effects, making it suitable for formulating oil-control toners, acne gels, and facial cleansers targeting oily and acne-prone skin.
Sensitive Skin Care: Its anti-inflammatory activity helps soothe skin irritation and redness, often incorporated into post-sun repair products and sensitive-skin care lines (at low concentrations to ensure safety).
1.3 Dietary Supplement Field
Weight Management Supplements: As a natural thermogenic ingredient, it is added to weight loss and fat-burning supplements (in compliance with dosage limits) to boost metabolism and promote fat oxidation.
Metabolic Health Support: Formulated into supplements for improving insulin sensitivity and regulating blood lipid levels, targeting populations with mild metabolic disorders (with clear dosage instructions and contraindication warnings).
QC Quality Control
| Test Item | Method | Standard |
|---|---|---|
| Purity | HPLC | ≥98.0% / ≥99.0% |
| Identity | LC-MS / NMR / FT-IR | Matches reference standard |
| Loss on Drying | Karl Fischer | ≤0.5% |
| Related Substances | HPLC | Total impurities ≤1.0% |
| Heavy Metals | ICP-MS | Meet research grade safety standard |
FAQ
| Question | Answer |
|---|---|
| Dissolution Method | Dissolve with DMSO or organic alcohol solvent |
| Core Advantage | Natural plant-derived, effective fat reduction and anti-inflammatory potency |
| MOQ & Sample | Small trial samples available, bulk supply supported |
| Supporting Documents | Complete COA, HPLC, MSDS documents |
| Shelf Life | 24 months under sealed cool dry dark storage |
Related products
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Yinherb Lab founded in 2009, has been deeply committed to the biotechnology field for over a decade. Today, it has established a professional development framework integrating "R&D + production" as an integrated system. And always adhered to the core business philosophy of "Quality First, Service Second, Price Third".
Our address
No.3, Daqing rd, Hi-tech zone, Xi'an city, China.
Phone Number
+8618681897250
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