Phenylpiracetam Hydrazide Powder CAS.77472-71-0 99% Purity
Product name: Phenylpiracetam Hydrazide
CAS No.: 77472-71-0
Molecular Formula: C₁₂H₁₅N₃O₂
Molecular Weight: 233.27 g/mol
Capacity: 500kgs per month
Source: synthetic
Purity (HPLC) >99.0%
Place of Origin: China Yinherb-Lab
Packing: As per client's requirements
Minimum Order Quantity: 1kg
Storage: Store in cool & dry place, Keep away from strong light and heat for 2 years
Description
Xi’an Yinherb Bio-Tech Co., Ltd. is one of the leading manufacturers and suppliers of phenylpiracetam hydrazide powder cas.77472-71-0 99% purity in China, also supports customized service. Welcome to buy bulk phenylpiracetam hydrazide powder cas.77472-71-0 99% purity for sale here from our factory. Quality products and reasonable price are available.
Leading Research lab on Nootropics & peptide in China
Yinherb Lab is a professional research Lab in china, have focused on Nutritional Supplements, Nootropics and Peptide raw materials researching and producing in this market for over 10 years with stable quality and great reputations, we can supply every batch test, including COA, HPLC and NMR. I believe that we must work well in future.
Yinherb Lab High Quality Phenylpiracetam Hydrazide Powder CAS.77472-71-0 99% Purity
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Product name |
Phenylpiracetam Hydrazide |
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Chemical name |
2-(2-oxo-4-phenylpyrrolidin-1-yl)acetohydrazide |
| Synonyms | Fonturacetam hydrazide, racetam phenylpiracetam hydrazide |
|
CAS No. |
77472-71-0 |
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Molecular formula |
C₁₂H₁₅N₃O₂ |
|
Molecular weight |
233.27 g/mol |
|
Purity |
≥98–99% (research grade, HPLC/LC-MS) |
|
Appearance |
White crystalline powder |
| Solubility | Soluble in water, ethanol; slightly soluble in ether |
| Melting Point | 154–155°C |
| Chirality | Racemic mixture (R/S isomers) |
| Storage | Room temperature (15–25°C), sealed, dark container |
|
Application |
Nootropic |
What is Phenylpiracetam Hydrazide Powder?
Phenylpiracetam Hydrazide Powder (CAS 77472-71-0, ≥99% HPLC) is a research-grade nootropic with a hydrazide modification that enhances bioavailability and blood–brain barrier penetration. It modulates glutamatergic, cholinergic, and dopaminergic systems to boost memory, focus, motivation, and neuroprotection. Ideal for cognitive neuroscience labs and CNS drug discovery, this high-purity powder delivers consistent, multimodal cognitive support for preclinical research.
Hydrazide Modification: Improved solubility, bioavailability, and BBB penetration vs. phenylpiracetam
High Purity: ≥99% HPLC-certified research-grade powder with strict impurity control
Multimodal Activity: Targets glutamatergic, cholinergic, and dopaminergic systems for balanced cognitive support
Stable Formulation: Crystalline structure with low moisture; robust batch consistency
Dual Focus: Investigated for both cognitive enhancement and neuroprotective/anticonvulsant properties
Phenylpiracetam Hydrazide Powder Mechanism of Action
PPH's mechanism differs from phenylpiracetam due to the hydrazide substitution, with a stronger focus on neuroprotection and anticonvulsant activity alongside mild cognitive enhancement:
Anticonvulsant Effects: Modulates GABAergic and glutamatergic systems to reduce excitotoxicity; ED₅₀ of 310 mg/kg in electroshock tests (preclinical).
Cholinergic & Glutamatergic Modulation: Mildly enhances acetylcholine release and NMDA/AMPA receptor sensitivity (weaker than phenylpiracetam).
Neuroprotection: Reduces oxidative stress and protects against ischemic damage (preclinical models).
Membrane Fluidity: Increases neuronal membrane fluidity (shared with most racetams), improving signal transduction.
Phenylpiracetam Hydrazide Powder Cognitive & Neuroprotective Effects
PPH is less potent for direct cognitive enhancement than phenylpiracetam but offers unique neuroprotective and anticonvulsant benefits:
| Effect Category | Details |
|---|---|
| Memory & Focus | Mild improvements in working memory and focus (weaker than phenylpiracetam/pramiracetam) |
| Anticonvulsant | Reduces seizure threshold in preclinical models (original research purpose) |
| Neuroprotection | Protects against TBI, ischemia, and oxidative stress |
| Mood & Anxiety | Minimal anxiolytic effects (unlike aniracetam); no significant mood modulation |
| Physical Performance | No known effects on stamina or physical endurance (unlike phenylpiracetam) |
QC Quality Control
| QC Item | Method | Standard |
|---|---|---|
| Purity | HPLC-UV/VIS | ≥99.0% |
| Identity | ¹H-NMR / LC-MS / FT-IR | Match reference spectrum |
| Moisture | Karl Fischer | ≤0.5% |
| Related Substances | HPLC | Total impurities ≤1.0% |
| Heavy Metals | AAS/ICP-MS | Meet research-grade safety limits |
| Melting Point | DSC | 154–155 ℃ (±1 ℃) |
PPH vs. Phenylpiracetam vs. Oxiracetam: Key Differences
| Feature | Phenylpiracetam Hydrazide (PPH) | Phenylpiracetam | Oxiracetam |
|---|---|---|---|
| Potency (Cognitive) | Low-Moderate | High | Moderate-High |
| Primary Effect | Neuroprotection + Anticonvulsant | Cognitive + Physical | Balanced Memory + Focus |
| Mechanism | GABA/glutamate-focused | Cholinergic + Glutamatergic | Cholinergic + Energy |
| Dosage Range | 300–900 mg/day | 100–300 mg/day | 800–2400 mg/day |
| Half-Life | ~2–3h | ~3–5h | ~2–3h |
| Safety Profile | Minimal side effects | Mild irritability (high doses) | Headache/GI (rare) |
| Best For | Neuroprotection, seizure models | Cognitive + physical performance | Balanced daily use |
Related products
Specized in Racetams, Sunifiram, Urolithin A/B, 9-Me-BC, Phenibut, L-Theanine, J-147, Noopept, phosphatidylserine, Alpha-GPC, CDP-Choline, etc.
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Yinherb Lab founded in 2009, has been deeply committed to the biotechnology field for over a decade. Today, it has established a professional development framework integrating "R&D + production" as an integrated system. And always adhered to the core business philosophy of "Quality First, Service Second, Price Third".
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